DEFB126

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DEFB126 protein abundance is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. OV shows the largest number of these associations.

The most reproducible DEFB126-associated genes across cancer lineages are MIR205HG, MCPH1-AS1, and TRBV24-1. Each is linked with DEFB126 in more than 1 cancer types. Because this analysis shows association rather than direction, both DEFB126-to-partner and partner-to-DEFB126 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DEFB126 versus MIR205HG in OV, with a Pearson correlation of -0.90.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DEFB126→partner) and Y-score (partner→DEFB126) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVMIR205HG →-2.370-1.011.004.00731
OVMCPH1-AS1 →-0.651-1.011.007.00731
OVTRBV24-1 →-0.377-1.011.009.00711
OVRPS15AP17 →-0.793-1.011.003.00711
OVSEPHS1P4 →-1.449-1.011.005.00711
OVH2BC15 →-1.093-1.011.005.00711
Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

DEFB126 vs MIR205HG — OV

Per-sample scatter of DEFB126 vs MIR205HG in OV (Pearson r = -0.90).

Explore this scatter interactively →

Exploration