DEFA11P

Across TCGA patient cohorts, DEFA11P RNA expression is significantly associated with the go_rna of many other GO terms, with 4,866 significant associations in total. STAD shows the largest number of these associations.

The most reproducible DEFA11P-associated GO terms across cancer lineages are Positive regulation of double-strand break repair, snRNA processing, and RNA 3'-end processing. Each is linked with DEFA11P in more than 4 cancer types. Because this analysis shows association rather than direction, both DEFA11P-to-partner and partner-to-DEFA11P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of double-strand break repair grouped by DEFA11P-low versus DEFA11P-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DEFA11P→partner) and Y-score (partner→DEFA11P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of double-strand break repair →	+0.139	+0.053	<.001	<.001	3	5
STAD	snRNA processing →	+0.125	+0.069	<.001	<.001	3	5
STAD	RNA 3'-end processing →	+0.141	+0.045	<.001	<.001	3	5
STAD	mRNA 3'-end processing →	+0.139	+0.071	<.001	<.001	3	5
STAD	snRNA 3'-end processing →	+0.117	+0.076	<.001	<.001	3	5
STAD	Negative regulation of binding →	+0.134	+0.048	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,866 associations by consensus.

Positive regulation of double-strand break repair by DEFA11P expression — STAD

Explore this box plot interactively →