DEFA10P

Across TCGA patient cohorts, DEFA10P RNA expression is significantly associated with the go_rna of many other GO terms, with 5,352 significant associations in total. KIRP shows the largest number of these associations.

The most reproducible DEFA10P-associated GO terms across cancer lineages are Regulation of DNA-templated transcription elongation, DNA methylation-dependent heterochromatin formation, and Obsolete histone H3-K4 methylation. Each is linked with DEFA10P in more than 6 cancer types. Because this analysis shows association rather than direction, both DEFA10P-to-partner and partner-to-DEFA10P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of DNA-templated transcription elongation grouped by DEFA10P-low versus DEFA10P-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DEFA10P→partner) and Y-score (partner→DEFA10P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of DNA-templated transcription elongation →	+0.112	+0.094	<.001	<.001	3	7
STAD	DNA methylation-dependent heterochromatin formation →	+0.097	+0.105	<.001	<.001	3	6
STAD	Obsolete histone H3-K4 methylation →	+0.107	+0.085	<.001	.001	3	6
STAD	Positive regulation of chromatin organization →	+0.099	+0.141	<.001	<.001	3	5
STAD	Regulation of exit from mitosis →	+0.089	+0.095	<.001	<.001	3	5
STAD	Positive regulation of cytoplasmic mRNA processing body assembly →	+0.072	+0.080	<.001	.003	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,352 associations by consensus.

Regulation of DNA-templated transcription elongation by DEFA10P expression — STAD

Explore this box plot interactively →