DDX59-AS1

Across TCGA patient cohorts, DDX59-AS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,058 significant associations in total. STAD shows the largest number of these associations.

The most reproducible DDX59-AS1-associated GO terms across cancer lineages are tRNA 3'-end processing, Mitochondrial cytochrome c oxidase assembly, and Protein insertion into mitochondrial inner membrane. Each is linked with DDX59-AS1 in more than 13 cancer types. Because this analysis shows association rather than direction, both DDX59-AS1-to-partner and partner-to-DDX59-AS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, tRNA 3'-end processing grouped by DDX59-AS1-low versus DDX59-AS1-high in GBM.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX59-AS1→partner) and Y-score (partner→DDX59-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	tRNA 3'-end processing →	+0.029	+0.715	<.001	<.001	2	14
STAD	Mitochondrial cytochrome c oxidase assembly →	+0.048	+0.247	<.001	<.001	3	11
STAD	Protein insertion into mitochondrial inner membrane →	+0.053	+0.298	<.001	<.001	3	10
ESCA	Regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning →	+0.067	+0.492	<.001	<.001	2	11
ESCA	mRNA 3'-splice site recognition →	+0.050	+0.372	<.001	<.001	3	10
STAD	Respiratory chain complex IV assembly →	+0.050	+0.212	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,058 associations by consensus.

tRNA 3'-end processing by DDX59-AS1 expression — GBM

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