DDX59-AS1

Across TCGA pan-cancer cohorts, DDX59-AS1 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated DDX59-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher DDX59-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated DDX59-AS1 expression acts as an unfavorable survival marker, although some lineages such as UVM and LGG show a favorable association.

KIRC, KIRP, and ACC are the cancer types where DDX59-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Quartile	All	0.492	0.737	<.001	67	view →
KIRP	DFS	Quartile	II,III,IV	0.358	0.771	<.001	57	view →
ACC	DFS	Quartile	All	0.164	0.613	.002	47	view →
LUAD	DFS	Tertile	II,III,IV	0.337	0.634	.001	46	view →
HNSC	OS	Quartile	All	0.330	0.563	.002	28	view →
KICH	DFS	Median	All	0.693	1.000	.008	23	view →
UVM	DFS	Median	III,IV	0.868	0.516	.023	14	view →
THCA	OS	Quartile	All	0.817	1.000	.022	13	view →
READ	OS	Quartile	III,IV	0.615	0.976	.008	7	view →
STAD	DFS	Median	IV	0.157	0.566	.003	6	view →
PRAD	DFS	Quartile	All	0.723	0.845	.023	6	view →
LIHC	OS	Tertile	All	0.426	0.637	.019	5	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

DDX59-AS1–KIRC (DFS)

Open the KIRC breakdown →