Across TCGA patient cohorts, DDX51 protein abundance is significantly associated with the RNA expression of many other genes, with 16,987 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DDX51-associated genes across cancer lineages are ZC3H8, AHCY, and SCN1B. Each is linked with DDX51 in more than 6 cancer types. Because this analysis shows association rather than direction, both DDX51-to-partner and partner-to-DDX51 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX51→partner) and Y-score (partner→DDX51) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ZC3H8 →	+0.441	+0.244	<.001	<.001	3	7
UCEC	AHCY →	+0.772	+0.127	<.001	.003	3	6
OV	SCN1B →	-0.636	-0.343	<.001	.003	3	6
BRCA	POLR3G →	+0.799	+0.313	<.001	<.001	3	6
BRCA	WDR74 →	+0.495	+0.198	<.001	<.001	3	6
BRCA	MYC →	+1.003	+0.254	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,987 associations by consensus.

Exploration

DDX51 survival (RNA) · tumor vs normal (RNA) · all DDX51 data types