Across TCGA cell cohorts, DDX51 mutation is significantly associated with the RNA expression of many other genes, with 481 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DDX51-associated genes across cancer lineages are AVP, G6PC, and SCN10A. Each is linked with DDX51 in more than 1 cancer types. Because this analysis shows association rather than direction, both DDX51-to-partner and partner-to-DDX51 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX51→partner) and Y-score (partner→DDX51) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	AVP →	+0.039	+5.794	<.001	<.001	3	1
CNS	G6PC →	+0.030	+3.700	<.001	.003	3	1
CNS	SCN10A →	+0.103	+3.459	<.001	.006	3	1
CNS	OR2T4 →	+0.056	+3.459	.009	.006	3	1
CNS	HSD3B2 →	+0.148	+3.449	<.001	.004	3	1
LARGE_INTESTINE	GCAT →	+1.074	+3.364	.008	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 481 associations by consensus.

Exploration

DDX51 survival (RNA) · tumor vs normal (RNA) · all DDX51 data types