DDX46

Across TCGA patient cohorts, DDX46 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,411 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DDX46-associated proteins across cancer lineages are PHAX, ZMAT2, and SMC4. Each is linked with DDX46 in more than 6 cancer types. Because this analysis shows association rather than direction, both DDX46-to-partner and partner-to-DDX46 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DDX46 versus PHAX in OV, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX46→partner) and Y-score (partner→DDX46) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PHAX →	+0.359	+0.513	<.001	<.001	3	7
GBM	ZMAT2 →	+0.283	+0.242	<.001	<.001	3	6
GBM	SMC4 →	+0.563	+0.326	.005	<.001	3	6
OV	KDM3B →	+0.310	+0.420	<.001	<.001	3	6
GBM	NASP →	+0.520	+0.259	<.001	<.001	3	6
GBM	SREK1 →	+0.264	+0.256	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,411 associations by consensus.

DDX46 vs PHAX — OV

Explore this scatter interactively →