Across TCGA patient cohorts, DDX3X protein abundance is significantly associated with the RNA expression of many other genes, with 11,931 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible DDX3X-associated genes across cancer lineages are CA5BP1, USP9Y, and USP9X. Each is linked with DDX3X in more than 7 cancer types. Because this analysis shows association rather than direction, both DDX3X-to-partner and partner-to-DDX3X results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX3X→partner) and Y-score (partner→DDX3X) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CA5BP1 →	+0.560	+0.227	<.001	<.001	3	8
PDAC	USP9Y →	-3.082	-0.318	<.001	<.001	3	7
OV	USP9X →	+0.692	+0.260	.008	.009	2	8
PDAC	KDM5D →	-3.484	-0.326	<.001	<.001	3	7
PDAC	RPS4Y1 →	-4.994	-0.308	<.001	<.001	3	7
PDAC	TXLNGY →	-3.294	-0.307	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,931 associations by consensus.

Exploration

DDX3X survival (RNA) · tumor vs normal (RNA) · all DDX3X data types