DDX39A

Across TCGA patient cohorts, DDX39A RNA expression is significantly associated with the protein abundance of many other proteins, with 22,527 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DDX39A-associated proteins across cancer lineages are MCM5, MCM7, and MKI67. Each is linked with DDX39A in more than 8 cancer types. Because this analysis shows association rather than direction, both DDX39A-to-partner and partner-to-DDX39A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DDX39A versus MCM5 in LUAD, with a Pearson correlation of 0.49.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX39A→partner) and Y-score (partner→DDX39A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	MCM5 →	+0.723	+0.491	<.001	<.001	3	9
UCEC	MCM7 →	+0.770	+1.131	<.001	<.001	3	9
BRCA	MKI67 →	+0.810	+0.792	<.001	<.001	3	9
UCEC	SMC2 →	+0.742	+1.208	<.001	.001	3	9
LUAD	SMC4 →	+0.611	+0.494	<.001	<.001	3	9
GBM	LIG1_S76 →	+0.772	+0.436	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 22,527 associations by consensus.

DDX39A vs MCM5 — LUAD

Explore this scatter interactively →