DDR1-DT

Across TCGA patient cohorts, DDR1-DT RNA expression is significantly associated with the go_rna of many other GO terms, with 6,716 significant associations in total. STAD shows the largest number of these associations.

The most reproducible DDR1-DT-associated GO terms across cancer lineages are Protein localization to mitochondrion, Regulation of double-strand break repair, and Protein targeting to membrane. Each is linked with DDR1-DT in more than 19 cancer types. Because this analysis shows association rather than direction, both DDR1-DT-to-partner and partner-to-DDR1-DT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to mitochondrion grouped by DDR1-DT-low versus DDR1-DT-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DDR1-DT→partner) and Y-score (partner→DDR1-DT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Protein localization to mitochondrion →	+0.055	+0.091	<.001	<.001	3	20
STAD	Regulation of double-strand break repair →	+0.052	+0.086	<.001	<.001	3	20
STAD	Protein targeting to membrane →	+0.052	+0.084	<.001	<.001	3	20
STAD	Nucleus organization →	+0.059	+0.092	<.001	<.001	3	20
ESCA	Protein polyubiquitination →	+0.079	+0.111	<.001	<.001	3	20
STAD	Regulation of protein ubiquitination →	+0.060	+0.097	<.001	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,716 associations by consensus.

Protein localization to mitochondrion by DDR1-DT expression — STAD

Explore this box plot interactively →