DDR1-DT

Across TCGA pan-cancer cohorts, DDR1-DT RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated DDR1-DT data layer.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher DDR1-DT RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated DDR1-DT expression acts as an unfavorable survival marker, although some lineages such as LUAD and SKCM show a favorable association.

LUAD, KIRC, and SKCM are the cancer types where DDR1-DT RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Median	III,IV	0.642	0.360	<.001	91	view →
KIRC	DFS	Quartile	III,IV	0.232	0.519	<.001	74	view →
SKCM	OS	Median	All	0.402	0.275	<.001	63	view →
UVM	OS	Tertile	All	0.280	0.758	<.001	45	view →
LUSC	OS	Quartile	All	0.866	0.713	<.001	36	view →
READ	DFS	Quartile	IV	0.190	0.691	<.001	35	view →
THYM	DFS	Median	III,IV	0.456	1.000	.006	26	view →
KIRP	DFS	Median	IV	0.035	0.428	.017	25	view →
UCS	DFS	Tertile	IV	0.318	0.799	.031	18	view →
LIHC	DFS	Tertile	All	0.291	0.487	.003	17	view →
BLCA	DFS	Median	All	0.439	0.258	.019	16	view →
MESO	DFS	Quartile	II,III,IV	0.488	0.234	.021	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

DDR1-DT–LUAD (DFS)

Open the LUAD breakdown →