DDIT4L

Across TCGA patient cohorts, DDIT4L RNA expression is significantly associated with the protein abundance of many other proteins, with 17,281 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible DDIT4L-associated proteins across cancer lineages are TBRG4, TLN2, and PGM1. Each is linked with DDIT4L in more than 5 cancer types. Because this analysis shows association rather than direction, both DDIT4L-to-partner and partner-to-DDIT4L results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DDIT4L versus TBRG4 in BRCA, with a Pearson correlation of -0.25.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DDIT4L→partner) and Y-score (partner→DDIT4L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TBRG4 →	-0.359	-0.739	<.001	.008	3	6
HNSC	TLN2 →	+0.512	+1.622	<.001	<.001	3	6
HNSC	PGM1 →	+0.485	+1.592	<.001	<.001	3	6
PDAC	CNN3 →	+0.678	+0.884	<.001	<.001	3	6
COAD	CSRP1 →	+0.860	+0.618	<.001	<.001	3	6
OV	FLNA →	+0.725	+2.260	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,281 associations by consensus.

DDIT4L vs TBRG4 — BRCA

Explore this scatter interactively →