DDIT4L

Across TCGA patient cohorts, DDIT4L mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DDIT4L-associated genes across cancer lineages are MEP and HSC. Each is linked with DDIT4L in more than 1 cancer types. Because this analysis shows association rather than direction, both DDIT4L-to-partner and partner-to-DDIT4L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MEP grouped by DDIT4L-low versus DDIT4L-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DDIT4L→partner) and Y-score (partner→DDIT4L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MEP →	+0.033	+2.909	.015	.030	3	1
UCEC	HSC →	+0.110	+3.021	.031	.018	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

MEP by DDIT4L expression — SKCM

Explore this box plot interactively →