DDIT4L

Across TCGA cell cohorts, DDIT4L RNA expression is significantly associated with the go_rna of many other GO terms, with 1,558 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DDIT4L-associated GO terms across cancer lineages are COPII-coated vesicle cargo loading, Epithelial structure maintenance, and Cellular respiration. Each is linked with DDIT4L in more than 7 cancer types. Because this analysis shows association rather than direction, both DDIT4L-to-partner and partner-to-DDIT4L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, COPII-coated vesicle cargo loading grouped by DDIT4L-low versus DDIT4L-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DDIT4L→partner) and Y-score (partner→DDIT4L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	COPII-coated vesicle cargo loading →	+0.050	+0.881	.006	.002	3	7
URINARY_TRACT	Epithelial structure maintenance →	-0.151	-1.244	.002	.003	3	7
SOFT_TISSUE	Cellular respiration →	+0.043	+0.668	.002	.006	3	6
OESOPHAGUS	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.098	+0.426	<.001	.006	3	6
LUNG_NSCLC_LUAD	Energy derivation by oxidation of organic compounds →	+0.040	+0.984	.008	.004	1	8
KIDNEY	Vesicle budding from membrane →	+0.049	+1.103	.008	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,558 associations by consensus.

COPII-coated vesicle cargo loading by DDIT4L expression — SOFT_TISSUE

Explore this box plot interactively →