DCUN1D5

Across TCGA patient cohorts, DCUN1D5 mutation is significantly associated with the RNA expression of many other genes, with 296 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DCUN1D5-associated genes across cancer lineages are SNORD11B, RNU6-6P, and FRG1HP. Each is linked with DCUN1D5 in more than 1 cancer types. Because this analysis shows association rather than direction, both DCUN1D5-to-partner and partner-to-DCUN1D5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNORD11B grouped by DCUN1D5-low versus DCUN1D5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DCUN1D5→partner) and Y-score (partner→DCUN1D5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SNORD11B →	+0.587	+2.476	<.001	.001	3	1
UCEC	RNU6-6P →	+0.549	+2.549	<.001	.001	3	1
UCEC	FRG1HP →	+0.620	+3.191	.001	.009	3	1
SKCM	RNU1-38P →	+0.287	+5.097	<.001	.008	3	1
SKCM	RNU4-68P →	+0.282	+4.979	<.001	.009	3	1
SKCM	PCDH9-AS3 →	+0.134	+5.594	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 296 associations by consensus.

SNORD11B by DCUN1D5 expression — UCEC

Explore this box plot interactively →