DCUN1D4

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DCUN1D4 mutation is significantly associated with the RNA expression of many other genes, with 4,346 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DCUN1D4-associated genes across cancer lineages are RNU6-110P, HMGN2P34, and LINC01486. Each is linked with DCUN1D4 in more than 1 cancer types. Because this analysis shows association rather than direction, both DCUN1D4-to-partner and partner-to-DCUN1D4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-110P grouped by DCUN1D4-low versus DCUN1D4-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DCUN1D4→partner) and Y-score (partner→DCUN1D4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADRNU6-110P →+0.778+4.181<.001.00932
COADHMGN2P34 →+0.391+4.510<.001.00532
COADLINC01486 →+0.180+4.993<.001.00232
LUADMIR1183 →+0.401+3.330.004.00832
UCECLINC02438 →+0.677+2.584<.001<.00132
BLCARNA5-8SP7 →+0.207+7.640<.001.00932
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,346 associations by consensus.

RNU6-110P by DCUN1D4 expression — COAD

Box plot of RNU6-110P in DCUN1D4-low vs DCUN1D4-high samples in COAD.

Explore this box plot interactively →

Exploration