DCUN1D4

Across TCGA cell cohorts, DCUN1D4 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible DCUN1D4-associated genes across cancer lineages are LIM2, ASCL4, and OR2B3. Each is linked with DCUN1D4 in more than 1 cancer types. Because this analysis shows association rather than direction, both DCUN1D4-to-partner and partner-to-DCUN1D4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LIM2 grouped by DCUN1D4-low versus DCUN1D4-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DCUN1D4→partner) and Y-score (partner→DCUN1D4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	LIM2 →	+0.019	+5.662	<.001	.002	3	1
LUNG_NSCLC_LUAD	ASCL4 →	+0.006	+5.228	.005	.005	3	1
LUNG_NSCLC_LUAD	OR2B3 →	+0.022	+5.228	<.001	.005	3	1
LUNG_NSCLC_LUAD	CXorf51A →	+0.055	+4.887	<.001	.009	3	1
SKIN	MAGEB4 →	+0.010	+5.022	<.001	.002	3	1
SKIN	PPP1R3A →	+0.041	+4.930	.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

LIM2 by DCUN1D4 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →