Across TCGA patient cohorts, DCTN1 mutation is significantly associated with the RNA expression of many other genes, with 5,176 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DCTN1-associated genes across cancer lineages are RNLS, AKR1A1, and OR4Q3. Each is linked with DCTN1 in more than 3 cancer types. Because this analysis shows association rather than direction, both DCTN1-to-partner and partner-to-DCTN1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DCTN1→partner) and Y-score (partner→DCTN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNLS →	-1.057	-3.459	<.001	.005	3	4
SKCM	AKR1A1 →	+0.411	+3.182	.007	.009	3	4
LUAD	OR4Q3 →	+0.017	+5.599	<.001	.001	3	3
UCEC	CCL5 →	+1.143	+1.980	<.001	<.001	3	3
SARC	FBP2P1 →	+0.086	+5.620	<.001	.004	3	3
LIHC	RNU7-11P →	+0.605	+5.355	<.001	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,176 associations by consensus.

Exploration

DCTN1 survival (RNA) · tumor vs normal (RNA) · all DCTN1 data types