DCTD

Across TCGA patient cohorts, DCTD protein abundance is significantly associated with the RNA expression of many other genes, with 6,738 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DCTD-associated genes across cancer lineages are UFSP2, RWDD4, and CFAP97. Each is linked with DCTD in more than 5 cancer types. Because this analysis shows association rather than direction, both DCTD-to-partner and partner-to-DCTD results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DCTD versus UFSP2 in OV, with a Pearson correlation of 0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DCTD→partner) and Y-score (partner→DCTD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	UFSP2 →	+0.457	+0.339	<.001	<.001	3	6
OV	RWDD4 →	+0.653	+0.488	<.001	<.001	3	6
OV	CFAP97 →	+0.716	+0.465	<.001	.001	3	5
LUAD	CLCN3 →	+0.610	+0.315	<.001	<.001	3	5
OV	TRAPPC11 →	+0.469	+0.322	<.001	<.001	3	5
BRCA	RWDD4P2 →	+0.612	+0.476	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,738 associations by consensus.

DCTD vs UFSP2 — OV

Explore this scatter interactively →