DCSTAMP

Across TCGA cell cohorts, DCSTAMP RNA expression is significantly associated with the go_rna of many other GO terms, with 1,136 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DCSTAMP-associated GO terms across cancer lineages are Viral gene expression, Regulation of excretion, and Chaperone-mediated autophagy. Each is linked with DCSTAMP in more than 4 cancer types. Because this analysis shows association rather than direction, both DCSTAMP-to-partner and partner-to-DCSTAMP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Viral gene expression grouped by DCSTAMP-low versus DCSTAMP-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DCSTAMP→partner) and Y-score (partner→DCSTAMP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Viral gene expression →	+0.060	+0.147	<.001	.009	3	4
SKIN	Regulation of excretion →	+0.830	+1.273	.009	.003	2	5
BONE	Chaperone-mediated autophagy →	+0.120	+0.143	.003	.007	3	4
SKIN	Negative regulation of T-helper 17 type immune response →	+0.093	+1.096	<.001	.001	3	4
BLOOD_Leukemia	Positive regulation of cell-substrate junction organization →	+0.040	+0.383	.008	.004	3	4
BONE	Indole-containing compound metabolic process →	-0.148	-0.147	<.001	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,136 associations by consensus.

Viral gene expression by DCSTAMP expression — BLOOD_Lymphoma

Explore this box plot interactively →