DCAF7

Across TCGA patient cohorts, DCAF7 mutation is significantly associated with the RNA expression of many other genes, with 923 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DCAF7-associated genes across cancer lineages are SNRPGP17, FGF7P5, and IGLJ7. Each is linked with DCAF7 in more than 1 cancer types. Because this analysis shows association rather than direction, both DCAF7-to-partner and partner-to-DCAF7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNRPGP17 grouped by DCAF7-low versus DCAF7-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DCAF7→partner) and Y-score (partner→DCAF7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SNRPGP17 →	+0.282	+2.142	<.001	<.001	3	2
LUAD	FGF7P5 →	+0.175	+6.087	<.001	.002	3	2
UCEC	IGLJ7 →	+0.904	+1.831	.002	.002	3	2
UCEC	RN7SKP286 →	+0.033	+3.738	<.001	.009	3	2
UCEC	AP1B1P1 →	+0.084	+1.823	<.001	.004	3	2
UCEC	FAM138E →	+0.021	+2.601	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 923 associations by consensus.

SNRPGP17 by DCAF7 expression — UCEC

Explore this box plot interactively →