DCAF6

Across TCGA patient cohorts, DCAF6 mutation is significantly associated with the RNA expression of many other genes, with 2,304 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DCAF6-associated genes across cancer lineages are NCAPH2, RASSF1, and TAPT1-AS1. Each is linked with DCAF6 in more than 2 cancer types. Because this analysis shows association rather than direction, both DCAF6-to-partner and partner-to-DCAF6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NCAPH2 grouped by DCAF6-low versus DCAF6-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DCAF6→partner) and Y-score (partner→DCAF6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NCAPH2 →	+0.533	+2.415	<.001	<.001	3	3
UCEC	RASSF1 →	+0.302	+1.925	.001	.004	3	3
UCEC	TAPT1-AS1 →	-0.260	-2.169	.007	.003	3	3
UCEC	DHDDS →	+0.377	+1.698	<.001	<.001	3	3
UCEC	PARP2 →	+0.348	+1.855	.002	.002	3	3
UCEC	TCF19 →	+0.477	+1.709	.006	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,304 associations by consensus.

NCAPH2 by DCAF6 expression — UCEC

Explore this box plot interactively →