DCAF6

Across TCGA cell cohorts, DCAF6 mutation is significantly associated with the RNA expression of many other genes, with 52 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DCAF6-associated genes across cancer lineages are DPRX, SYNPR, and SOX14. Each is linked with DCAF6 in more than 1 cancer types. Because this analysis shows association rather than direction, both DCAF6-to-partner and partner-to-DCAF6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DPRX grouped by DCAF6-low versus DCAF6-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DCAF6→partner) and Y-score (partner→DCAF6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	DPRX →	+0.082	+4.060	<.001	.003	3	2
SOFT_TISSUE	SYNPR →	+0.435	+3.736	<.001	.008	3	1
SOFT_TISSUE	SOX14 →	+0.743	+3.882	<.001	.004	3	1
SOFT_TISSUE	PCDH11Y →	+1.626	+3.865	<.001	.006	3	1
LARGE_INTESTINE	HINT3 →	+0.634	+3.364	.006	.002	3	1
LARGE_INTESTINE	BEST3 →	+0.544	+3.131	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 52 associations by consensus.

DPRX by DCAF6 expression — BLOOD_Leukemia

Explore this box plot interactively →