Across TCGA cell cohorts, DBX2 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DBX2-associated genes across cancer lineages are SCN10A, GAPDHS, and SPEM1. Each is linked with DBX2 in more than 1 cancer types. Because this analysis shows association rather than direction, both DBX2-to-partner and partner-to-DBX2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DBX2→partner) and Y-score (partner→DBX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	SCN10A →	+0.004	+4.662	<.001	.005	3	1
LARGE_INTESTINE	GAPDHS →	+0.066	+3.626	<.001	.006	3	1
LARGE_INTESTINE	SPEM1 →	+0.115	+3.347	<.001	.005	3	1
LARGE_INTESTINE	OR2J2 →	+0.010	+3.632	.005	.003	3	1
LARGE_INTESTINE	TBC1D3 →	+0.061	+3.688	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

DBX2 survival (RNA) · tumor vs normal (RNA) · all DBX2 data types