DBI

Across TCGA patient cohorts, DBI RNA expression is significantly associated with the protein abundance of many other proteins, with 15,186 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DBI-associated proteins across cancer lineages are HMGCS1, FDFT1, and SMC4. Each is linked with DBI in more than 7 cancer types. Because this analysis shows association rather than direction, both DBI-to-partner and partner-to-DBI results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DBI versus HMGCS1 in HNSC, with a Pearson correlation of 0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DBI→partner) and Y-score (partner→DBI) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	HMGCS1 →	+0.725	+0.741	<.001	<.001	3	8
HNSC	FDFT1 →	+0.958	+0.859	<.001	<.001	3	6
GBM	SMC4 →	+0.613	+0.711	.002	.001	3	5
HNSC	ADI1 →	+0.412	+0.739	<.001	<.001	3	5
HNSC	ZC3H15 →	+0.265	+0.819	.002	<.001	3	5
GBM	NCAPG →	+0.530	+0.657	.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,186 associations by consensus.

DBI vs HMGCS1 — HNSC

Explore this scatter interactively →