DBF4B

Across TCGA patient cohorts, DBF4B protein abundance is significantly associated with the RNA expression of many other genes, with 233 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DBF4B-associated genes across cancer lineages are ZFYVE21, AHCY, and MYOM1. Each is linked with DBF4B in more than 1 cancer types. Because this analysis shows association rather than direction, both DBF4B-to-partner and partner-to-DBF4B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DBF4B versus ZFYVE21 in GBM, with a Pearson correlation of 0.61.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DBF4B→partner) and Y-score (partner→DBF4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ZFYVE21 →	+0.518	+0.902	.004	<.001	3	1
GBM	AHCY →	-0.578	-1.059	.001	.001	3	1
GBM	MYOM1 →	+1.349	+1.021	.006	.001	3	1
GBM	TSC22D1 →	+0.891	+0.782	<.001	.004	3	1
GBM	PLLP →	+1.650	+1.066	.009	.002	3	1
GBM	CCN4 →	-2.649	-1.010	.005	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 233 associations by consensus.

DBF4B vs ZFYVE21 — GBM

Explore this scatter interactively →