DBF4B

Across TCGA patient cohorts, DBF4B mutation is significantly associated with the RNA expression of many other genes, with 4,190 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DBF4B-associated genes across cancer lineages are ZNF736P7Y, DGAT2, and LINC02559. Each is linked with DBF4B in more than 3 cancer types. Because this analysis shows association rather than direction, both DBF4B-to-partner and partner-to-DBF4B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZNF736P7Y grouped by DBF4B-low versus DBF4B-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DBF4B→partner) and Y-score (partner→DBF4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	ZNF736P7Y →	+0.063	+3.376	<.001	.003	3	4
COAD	DGAT2 →	-0.600	-3.700	.007	.001	3	3
CESC	LINC02559 →	+0.674	+4.342	<.001	.007	3	3
UCEC	KIAA0930 →	+0.502	+1.981	<.001	<.001	3	3
HNSC	NBPF5P →	+0.020	+4.912	.001	.005	3	3
LUSC	PUS3 →	+0.378	+3.223	.004	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,190 associations by consensus.

ZNF736P7Y by DBF4B expression — COAD

Explore this box plot interactively →