DBF4B

Across TCGA cell cohorts, DBF4B RNA expression is significantly associated with the go_rna of many other GO terms, with 5,290 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DBF4B-associated GO terms across cancer lineages are Microtubule organizing center organization, Interstrand cross-link repair, and Positive regulation of cell cycle. Each is linked with DBF4B in more than 19 cancer types. Because this analysis shows association rather than direction, both DBF4B-to-partner and partner-to-DBF4B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Microtubule organizing center organization grouped by DBF4B-low versus DBF4B-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DBF4B→partner) and Y-score (partner→DBF4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Microtubule organizing center organization →	+0.080	+1.062	<.001	<.001	3	20
UPPER_AERODIGESTIVE_TRACT	Interstrand cross-link repair →	+0.082	+1.282	<.001	.001	3	20
UPPER_AERODIGESTIVE_TRACT	Positive regulation of cell cycle →	+0.081	+1.450	<.001	<.001	3	20
OESOPHAGUS	Kinetochore assembly →	+0.232	+1.268	.001	<.001	3	20
OESOPHAGUS	Kinetochore organization →	+0.234	+1.132	<.001	.007	3	20
UPPER_AERODIGESTIVE_TRACT	DNA recombination →	+0.093	+1.432	<.001	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,290 associations by consensus.

Microtubule organizing center organization by DBF4B expression — LARGE_INTESTINE

Explore this box plot interactively →