DBF4

Across TCGA patient cohorts, DBF4 RNA expression is significantly associated with the protein abundance of many other proteins, with 23,328 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DBF4-associated proteins across cancer lineages are MKI67_S357, RRM2, and HAT1. Each is linked with DBF4 in more than 9 cancer types. Because this analysis shows association rather than direction, both DBF4-to-partner and partner-to-DBF4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DBF4 versus MKI67_S357 in LUAD, with a Pearson correlation of 0.55.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DBF4→partner) and Y-score (partner→DBF4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	MKI67_S357 →	+1.575	+0.693	<.001	<.001	3	10
LUAD	RRM2 →	+0.845	+0.759	<.001	<.001	3	10
LSCC	HAT1 →	+0.529	+0.889	<.001	<.001	3	10
LUAD	KPNA2 →	+0.666	+0.720	<.001	<.001	3	10
GBM	LIG1_S76 →	+0.961	+0.905	<.001	<.001	3	10
UCEC	SMC2 →	+0.718	+0.815	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 23,328 associations by consensus.

DBF4 vs MKI67_S357 — LUAD

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