DBF4

Across TCGA patient cohorts, DBF4 protein abundance is significantly associated with the RNA expression of many other genes, with 517 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DBF4-associated genes across cancer lineages are CHADL, ELL, and NIT2. Each is linked with DBF4 in more than 1 cancer types. Because this analysis shows association rather than direction, both DBF4-to-partner and partner-to-DBF4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DBF4 versus CHADL in UCEC, with a Pearson correlation of 0.98.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DBF4→partner) and Y-score (partner→DBF4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CHADL →	+1.115	+1.185	.008	.002	3	1
UCEC	ELL →	+1.184	+1.185	.009	.002	3	1
UCEC	NIT2 →	+0.644	+1.185	<.001	.002	3	1
UCEC	QPCTL →	+1.550	+1.185	.005	.002	3	1
UCEC	PHF19 →	+1.140	+1.185	.002	.002	3	1
UCEC	GNMT →	+3.364	+1.185	.005	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 517 associations by consensus.

DBF4 vs CHADL — UCEC

Explore this scatter interactively →