Across TCGA patient cohorts, DAXX RNA expression is significantly associated with the protein abundance of many other proteins, with 11,310 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DAXX-associated proteins across cancer lineages are GNL1, NUP153, and MSH2. Each is linked with DAXX in more than 5 cancer types. Because this analysis shows association rather than direction, both DAXX-to-partner and partner-to-DAXX results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DAXX→partner) and Y-score (partner→DAXX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	GNL1 →	+0.433	+0.830	<.001	<.001	3	6
OV	NUP153 →	+0.345	+0.676	<.001	<.001	3	6
LSCC	MSH2 →	+0.431	+0.334	<.001	<.001	3	6
OV	CMTR1 →	+0.293	+0.404	<.001	<.001	3	6
OV	ABCF1 →	+0.288	+0.445	<.001	<.001	3	6
GBM	NASP →	+0.524	+0.251	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,310 associations by consensus.

Exploration

DAXX survival (RNA) · tumor vs normal (RNA) · all DAXX data types