DAPL1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DAPL1 protein abundance is significantly associated with the RNA expression of many other genes, with 4,536 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DAPL1-associated genes across cancer lineages are OR7E89P, OR7E28P, and INPP4B. Each is linked with DAPL1 in more than 2 cancer types. Because this analysis shows association rather than direction, both DAPL1-to-partner and partner-to-DAPL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DAPL1 versus OR7E89P in LSCC, with a Pearson correlation of 0.76.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DAPL1→partner) and Y-score (partner→DAPL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCOR7E89P →+0.951+1.909<.001<.00133
LSCCOR7E28P →+0.826+2.060<.001<.00133
BRCAINPP4B →-1.876-1.508.002.00333
LSCCASPG →+1.028+1.485<.001<.00133
OVRASD1 →-1.285-0.836.007.00832
LSCCTPD52L1 →+0.659+0.901<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,536 associations by consensus.

DAPL1 vs OR7E89P — LSCC

Per-sample scatter of DAPL1 vs OR7E89P in LSCC (Pearson r = 0.76).

Explore this scatter interactively →

Exploration