olfactory receptor family 7 subfamily E member 28 pseudogeneGenealiases: OR7E107P · OR7E133P · OR7E27P · OST128 · hg616
Q-omics provides the consensus-scored OR7E28P profile across patient tissues and cancer cell-line models. OR7E28P expression is associated with patient survival in 17 of 34 cancer types, with the highest sampling consensus in HNSC. Among the 18 cancer types available for tumor–normal comparison, OR7E28P is differentially expressed in 10, with the highest sampling consensus in LUSC. Additionally, OR7E28P RNA expression shows 8,006 significant gene co-expression associations, with the highest sampling consensus in TGCT. Together, these results highlight HNSC, LUSC, and TGCT as cancer lineages where OR7E28P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for OR7E28P — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes OR7E28P survival associations across molecular data types. OR7E28P RNA expression shows survival associations in the most cancer types (17). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible OR7E28P RNA expression–survival associations across cancer types. High OR7E28P expression shows unfavorable associations in BLCA, but favorable associations in HNSC, LGG, BRCA, LUSC and GBM. The HNSC Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p = .003). Together, the overview and detailed table identify HNSC as the clearest survival context for OR7E28P RNA expression.
This table summarizes OR7E28P tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 10. The strongest signals are observed in LUSC for RNA.
This table ranks reproducible tumor–normal expression differences for OR7E28P. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. OR7E28P shows lower tumor expression in BRCA, HNSC, KICH and KIRC and higher tumor expression in LUSC and THCA. The LUSC box plot shows higher OR7E28P RNA expression in tumor versus normal tissue (log2 FC = +0.687, t-test p < 0.001).
This table shows molecular features associated with OR7E28P in patient tissues and cancer cell lines. In patient samples, OR7E28P shows the broadest associations at the RNA and protein expression levels, with TGCT recurring as the lineage with the largest associated feature set.
