OR7E28P

Across TCGA pan-cancer cohorts, OR7E28P RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of OR7E28P’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where OR7E28P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types OR7E28P is over-expressed in tumor, although a few such as BRCA and HNSC show the opposite, repressed pattern.

LUSC, BRCA, and HNSC are the cancer types where OR7E28P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in OR7E28P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	All	All	+0.687	<.001	6	view →
BRCA	All	All	−0.160	<.001	6	view →
HNSC	All	II,III,IV	−0.241	.001	5	view →
THCA	All	All	+0.363	<.001	3	view →
KICH	Female	All	−0.066	.006	3	view →
KIRC	All	II,III,IV	−0.029	.008	3	view →
UCEC	All	All	−0.413	.010	2	view →
PRAD	All	All	−0.145	<.001	2	view →
BLCA	Male	All	−0.131	.047	2	view →
LUAD	Female	III,IV	−0.055	.029	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

OR7E28P–LUSC

Open the LUSC breakdown →