DAP3

Across TCGA patient cohorts, DAP3 mutation is significantly associated with the RNA expression of many other genes, with 358 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DAP3-associated genes across cancer lineages are LINC02071, RNU4-58P, and RNA5SP232. Each is linked with DAP3 in more than 1 cancer types. Because this analysis shows association rather than direction, both DAP3-to-partner and partner-to-DAP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02071 grouped by DAP3-low versus DAP3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DAP3→partner) and Y-score (partner→DAP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LINC02071 →	+0.090	+2.562	.007	<.001	3	2
UCEC	RNU4-58P →	+0.233	+2.548	<.001	.007	3	2
UCEC	RNA5SP232 →	+0.139	+4.671	<.001	.002	3	2
UCEC	RNU6-990P →	+0.231	+3.220	<.001	.005	3	2
UCEC	CDC42P2 →	+0.124	+2.101	.009	.003	3	2
UCEC	FAM197Y6 →	+0.015	+3.928	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 358 associations by consensus.

LINC02071 by DAP3 expression — UCEC

Explore this box plot interactively →