DAND5

Across TCGA patient cohorts, DAND5 mutation is significantly associated with the RNA expression of many other genes, with 261 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DAND5-associated genes across cancer lineages are ICE2, SBNO1, and CEBPZOS. Each is linked with DAND5 in more than 1 cancer types. Because this analysis shows association rather than direction, both DAND5-to-partner and partner-to-DAND5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ICE2 grouped by DAND5-low versus DAND5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DAND5→partner) and Y-score (partner→DAND5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ICE2 →	+0.556	+3.354	.006	.005	3	2
UCEC	SBNO1 →	+0.638	+3.354	.004	.005	3	2
UCEC	CEBPZOS →	+0.494	+3.364	.004	.005	3	2
UCEC	LINC01792 →	+0.063	+2.442	.009	.005	3	2
UCEC	EEF1A1P31 →	+0.207	+3.166	<.001	.002	3	2
SKCM	RNU6-1318P →	+0.230	+3.292	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 261 associations by consensus.

ICE2 by DAND5 expression — UCEC

Explore this box plot interactively →