DAND5

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DAND5 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible DAND5-associated genes across cancer lineages are Neurons, Macrophages M2, and CLP. Each is linked with DAND5 in more than 1 cancer types. Because this analysis shows association rather than direction, both DAND5-to-partner and partner-to-DAND5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Neurons grouped by DAND5-low versus DAND5-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DAND5→partner) and Y-score (partner→DAND5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMNeurons →-0.021-2.980.045.03731
UCECMacrophages M2 →+0.012+2.831.029.03531
SKCMCLP →+0.104+3.019.020.01911
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Neurons by DAND5 expression — SKCM

Box plot of Neurons in DAND5-low vs DAND5-high samples in SKCM.

Explore this box plot interactively →

Exploration