DAND5

Across TCGA cell cohorts, DAND5 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,950 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DAND5-associated GO terms across cancer lineages are Positive regulation of intracellular steroid hormone receptor signaling pathway, Telomere maintenance, and Regulation of glycolytic process through fructose-6-phosphate. Each is linked with DAND5 in more than 8 cancer types. Because this analysis shows association rather than direction, both DAND5-to-partner and partner-to-DAND5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of intracellular steroid hormone receptor signaling pathway grouped by DAND5-low versus DAND5-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DAND5→partner) and Y-score (partner→DAND5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.111	+0.152	<.001	<.001	3	8
OVARY	Telomere maintenance →	+0.061	+0.191	.003	.002	3	8
BREAST	Regulation of glycolytic process through fructose-6-phosphate →	+0.184	+0.524	<.001	<.001	3	8
BREAST	Negative regulation of glycolytic process through fructose-6-phosphate →	+0.184	+0.524	<.001	<.001	3	8
BREAST	Negative regulation of syncytium formation by plasma membrane fusion →	+0.093	+0.288	<.001	<.001	3	8
BREAST	Interleukin-23-mediated signaling pathway →	+0.153	+0.289	.001	.002	2	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,950 associations by consensus.

Positive regulation of intracellular steroid hormone receptor signaling pathway by DAND5 expression — OVARY

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