DAND5

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, DAND5 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible DAND5-associated genes across cancer lineages are SPATA31D4 and KLRF2. Each is linked with DAND5 in more than 1 cancer types. Because this analysis shows association rather than direction, both DAND5-to-partner and partner-to-DAND5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SPATA31D4 grouped by DAND5-low versus DAND5-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DAND5→partner) and Y-score (partner→DAND5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BREASTSPATA31D4 →+0.023+5.169<.001.00531
BREASTKLRF2 →+0.063+5.781<.001.00131
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

SPATA31D4 by DAND5 expression — BREAST

Box plot of SPATA31D4 in DAND5-low vs DAND5-high samples in BREAST.

Explore this box plot interactively →

Exploration