DAB2

Across TCGA patient cohorts, DAB2 mutation is significantly associated with the RNA expression of many other genes, with 4,864 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DAB2-associated genes across cancer lineages are RNA5SP198, MIR3661, and PARP2. Each is linked with DAB2 in more than 3 cancer types. Because this analysis shows association rather than direction, both DAB2-to-partner and partner-to-DAB2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP198 grouped by DAB2-low versus DAB2-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DAB2→partner) and Y-score (partner→DAB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RNA5SP198 →	+0.218	+4.559	<.001	.006	3	4
COAD	MIR3661 →	+1.501	+3.829	<.001	.005	3	3
SKCM	PARP2 →	+0.503	+2.925	.001	.001	3	3
UCEC	GMNN →	+0.500	+3.807	.001	<.001	3	3
UCEC	FARSB →	+0.303	+1.898	.001	.001	3	3
UCEC	MRPS18BP2 →	+0.061	+1.501	.006	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,864 associations by consensus.

RNA5SP198 by DAB2 expression — CESC

Explore this box plot interactively →