CYTH3

Across TCGA patient cohorts, CYTH3 mutation is significantly associated with the RNA expression of many other genes, with 1,907 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CYTH3-associated genes across cancer lineages are RN7SL250P, MIR3661, and VCY. Each is linked with CYTH3 in more than 2 cancer types. Because this analysis shows association rather than direction, both CYTH3-to-partner and partner-to-CYTH3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL250P grouped by CYTH3-low versus CYTH3-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYTH3→partner) and Y-score (partner→CYTH3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RN7SL250P →	+0.088	+3.140	<.001	.008	3	3
UCEC	MIR3661 →	+0.528	+1.594	.001	.004	3	2
HNSC	VCY →	+0.099	+7.954	<.001	.008	3	2
HNSC	MIR668 →	+0.396	+7.954	<.001	.008	3	2
BRCA	WBP1LP7 →	+0.045	+7.057	<.001	.009	3	2
SKCM	MIR3666 →	+0.164	+3.291	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,907 associations by consensus.

RN7SL250P by CYTH3 expression — SKCM

Explore this box plot interactively →