Across TCGA patient cohorts, CYS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,880 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CYS1-associated proteins across cancer lineages are TLN2, PPFIBP1, and SGCD. Each is linked with CYS1 in more than 8 cancer types. Because this analysis shows association rather than direction, both CYS1-to-partner and partner-to-CYS1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CYS1→partner) and Y-score (partner→CYS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TLN2 →	+0.679	+1.315	<.001	<.001	3	9
BRCA	PPFIBP1 →	+0.402	+1.109	<.001	<.001	3	9
BRCA	SGCD →	+0.733	+1.306	<.001	<.001	3	8
GBM	DNM1 →	+0.681	+0.546	<.001	.001	3	8
COAD	AKT3 →	+1.093	+1.402	<.001	<.001	3	8
OV	MAP1A →	+0.463	+1.170	<.001	.003	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,880 associations by consensus.

Exploration

CYS1 survival (RNA) · tumor vs normal (RNA) · all CYS1 data types