Across TCGA patient cohorts, CYS1 protein abundance is significantly associated with the RNA expression of many other genes, with 790 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible CYS1-associated genes across cancer lineages are NPM1P27, ACCS, and PACRG-AS2. Each is linked with CYS1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CYS1-to-partner and partner-to-CYS1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYS1→partner) and Y-score (partner→CYS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	NPM1P27 →	-0.911	-0.331	.002	.006	3	2
UCEC	ACCS →	-0.470	-0.696	.005	.007	3	1
UCEC	PACRG-AS2 →	-0.632	-0.562	.004	.002	3	1
UCEC	LINC01781 →	+1.814	+0.743	.007	.007	3	1
UCEC	GAPDHP51 →	-0.592	-0.897	.003	.003	3	1
UCEC	RN7SL181P →	+0.932	+0.692	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 790 associations by consensus.

Exploration

CYS1 survival (RNA) · tumor vs normal (RNA) · all CYS1 data types