CYRIA

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CYRIA RNA expression is significantly associated with the protein abundance of many other proteins, with 18,967 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CYRIA-associated proteins across cancer lineages are TBC1D2B, PLEKHO2, and RASA3. Each is linked with CYRIA in more than 8 cancer types. Because this analysis shows association rather than direction, both CYRIA-to-partner and partner-to-CYRIA results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CYRIA→partner) and Y-score (partner→CYRIA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVTBC1D2B →+0.463+0.738<.001<.00139
OVPLEKHO2 →+0.473+0.780<.001<.00139
OVRASA3 →+0.601+0.704.001<.00139
COADVAMP5 →+0.510+0.675.001<.00138
BRCAVIM →+0.540+0.768<.001<.00138
HNSCRCSD1 →+0.528+0.580<.001<.00138
Each partner links to its Q-omics profile. Showing the 6 strongest of 18,967 associations by consensus.

Exploration