CYP4F62P

Across TCGA patient cohorts, CYP4F62P mutation is significantly associated with the RNA expression of many other genes, with 20 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CYP4F62P-associated genes across cancer lineages are RNU105C, RNU4-58P, and RNU5E-8P. Each is linked with CYP4F62P in more than 1 cancer types. Because this analysis shows association rather than direction, both CYP4F62P-to-partner and partner-to-CYP4F62P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU105C grouped by CYP4F62P-low versus CYP4F62P-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP4F62P→partner) and Y-score (partner→CYP4F62P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU105C →	+0.258	+5.484	<.001	.005	3	1
UCEC	RNU4-58P →	+0.463	+5.133	.002	.008	3	1
UCEC	RNU5E-8P →	+1.112	+5.186	<.001	.007	3	1
UCEC	RNA5SP447 →	+0.951	+5.133	<.001	.008	3	1
UCEC	RNA5SP130 →	+2.584	+4.982	<.001	.009	3	1
UCEC	RNA5SP172 →	+1.673	+5.771	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

RNU105C by CYP4F62P expression — UCEC

Explore this box plot interactively →