CYP4F27P

Across TCGA patient cohorts, CYP4F27P RNA expression is significantly associated with the go_rna of many other GO terms, with 6,493 significant associations in total. THYM shows the largest number of these associations.

The most reproducible CYP4F27P-associated GO terms across cancer lineages are Regulation of telomere maintenance via telomere lengthening, RNA-templated DNA biosynthetic process, and Regulation of double-strand break repair via homologous recombination. Each is linked with CYP4F27P in more than 17 cancer types. Because this analysis shows association rather than direction, both CYP4F27P-to-partner and partner-to-CYP4F27P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of telomere maintenance via telomere lengthening grouped by CYP4F27P-low versus CYP4F27P-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP4F27P→partner) and Y-score (partner→CYP4F27P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Regulation of telomere maintenance via telomere lengthening →	+0.048	+0.318	<.001	<.001	3	18
ESCA	RNA-templated DNA biosynthetic process →	+0.050	+0.314	<.001	<.001	3	18
ESCA	Regulation of double-strand break repair via homologous recombination →	+0.041	+0.263	<.001	<.001	3	18
ESCA	Peptidyl-lysine modification →	+0.043	+0.326	<.001	<.001	3	18
ESCA	Protein-containing complex localization →	+0.039	+0.306	<.001	<.001	3	18
STAD	Telomere organization →	+0.046	+0.185	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,493 associations by consensus.

Regulation of telomere maintenance via telomere lengthening by CYP4F27P expression — ESCA

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