CYP4F24P

Across TCGA patient cohorts, CYP4F24P mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CYP4F24P-associated genes across cancer lineages are RSU1P3, UBE2V1P15, and HTN3. Each is linked with CYP4F24P in more than 1 cancer types. Because this analysis shows association rather than direction, both CYP4F24P-to-partner and partner-to-CYP4F24P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RSU1P3 grouped by CYP4F24P-low versus CYP4F24P-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP4F24P→partner) and Y-score (partner→CYP4F24P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RSU1P3 →	+0.110	+5.159	<.001	.007	3	1
SKCM	UBE2V1P15 →	+0.192	+4.979	<.001	.009	3	1
UCEC	HTN3 →	+0.147	+3.903	.002	.006	3	1
UCEC	TRAJ11 →	+0.806	+4.813	.003	.001	3	1
UCEC	TRGVA →	+0.482	+4.717	<.001	.001	3	1
UCEC	KRTAP19-7 →	+0.214	+4.267	.002	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

RSU1P3 by CYP4F24P expression — SKCM

Explore this box plot interactively →