CYP4F24P

Across TCGA pan-cancer cohorts, CYP4F24P RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of CYP4F24P’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where CYP4F24P RNA is repressed in tumor relative to normal tissue. In most cancer types CYP4F24P is over-expressed in tumor, although a few such as COAD and KIRP show the opposite, repressed pattern.

COAD, KIRP, and HNSC are the cancer types where CYP4F24P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CYP4F24P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	III,IV	−0.542	<.001	10	view →
KIRP	All	All	−0.113	<.001	7	view →
HNSC	Male	All	−0.078	<.001	7	view →
UCEC	All	All	−1.046	<.001	6	view →
BRCA	All	III,IV	−0.948	<.001	6	view →
LUSC	Male	II,III,IV	−0.535	<.001	5	view →
LUAD	All	All	−0.247	.003	3	view →
READ	All	All	−0.530	.027	2	view →
PRAD	All	All	−0.179	.030	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

CYP4F24P–COAD

Open the COAD breakdown →