CYP4F24P

Across TCGA pan-cancer cohorts, CYP4F24P RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated CYP4F24P data layer.

The strongest signal is observed in thymoma (THYM), where higher CYP4F24P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated CYP4F24P expression acts as an unfavorable survival marker, although some lineages such as READ and PAAD show a favorable association.

THYM, READ, and KIRC are the cancer types where CYP4F24P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THYM	DFS	Tertile	All	0.680	0.976	<.001	46	view →
READ	OS	Tertile	All	0.911	0.492	.002	40	view →
KIRC	DFS	Median	All	0.532	0.696	<.001	38	view →
COAD	DFS	Tertile	II,III,IV	0.549	0.740	.009	38	view →
THCA	OS	Quartile	III,IV	0.690	0.922	.002	32	view →
PAAD	DFS	Median	All	0.365	0.189	.003	29	view →
SARC	DFS	Median	All	0.646	0.429	.001	27	view →
SKCM	DFS	Median	All	0.679	0.564	<.001	24	view →
LAML	DFS	Tertile	All	0.591	0.317	<.001	24	view →
LUAD	OS	Median	All	0.850	0.772	.006	20	view →
ACC	DFS	Quartile	II,III,IV	0.819	0.502	.013	17	view →
UCS	DFS	Quartile	III,IV	0.458	0.092	.024	14	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

CYP4F24P–THYM (DFS)

Open the THYM breakdown →